What is the primary psychoactive component in marijuana? Question What is the primary psychoactive component in marijuana? Answers THC TMJ MRT AAP Explanation The main psychoactive substance in marijuana is called tetrahydrocannabinol, or THC. This questions appears in the following tests: Colorado Motorcycle Practice Test 9 Connecticut Motorcycle Practice Test 9 District Of Columbia Motorcycle Practice Test 18 Iowa Motorcycle Practice Test 22 Maine Motorcycle Practice Test 30 Massachusetts Motorcycle Practice Test 2 Minnesota Motorcycle Practice Test 25 Montana Motorcycle Practice Test 17 Nevada Motorcycle Practice Test 25 New Hampshire Motorcycle Practice Test 19 New Jersey Motorcycle Practice Test 9 New Mexico Motorcycle Practice Test 9 North Dakota Motorcycle Practice Test 13 Oregon Motorcycle Practice Test 3 Texas Motorcycle Practice Test 17 Vermont Motorcycle Practice Test 4 West Virginia Motorcycle Practice Test 21